Protein fouling forms below about 110 degrees and mineral fouling forms above it
The two deposits found on dairy heat transfer surfaces behave differently enough that they are treated as separate problems. The lower-temperature layer is protein-rich, soft, voluminous and dominated by denatured whey protein. It forms through the heating section and it responds to caustic. The higher-temperature layer is hard, granular and mostly calcium phosphate, it forms in the hottest sections and holding tubes, and caustic does very little to it. Most packs carry both, in different places, so a single-chemistry cycle always leaves something behind.
